20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19309L1 | Endothelin 1 (swine, human) acetate | Endothelin 1 (swine, human) acetate(117399-94-7 free base) | Endothelin Receptor |
Endothelin 1 (swine, human) acetate is a synthetic peptide with the sequence of human and swine Endothelin 1. Endothelin 1 is a potent endogenous vasoconstrictor and acts through two types of receptors ETA and ETB. | |||
T22540L | Ac-Endothelin-1 (16-21), human acetate | Others | |
Ac-Endothelin-1 (16-21), human acetate, the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which i... | |||
T36480 | Big Endothelin-1 (1-39), porcine | ||
The big endothelins comprise residues 53-90 (human big ET-1) and 53-91 (porcine big ET-1) of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (ET-1), both peptides show less vasoconstricto... | |||
T19309 | Endothelin 1 (swine, human) | Others | |
Endothelin 1 (swine, human), a synthetic peptide mirroring the sequence of both human and swine Endothelin 1, functions as a robust endogenous vasoconstrictor by interacting with two receptor types, ETA and ETB. | |||
T22540 | Ac-Endothelin-1 (16-21), human | Others | |
ENDOTHELIN-1 (ET-1), the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which is a highly cons... | |||
TP2246 | Endothelin-1 (1-15), amide, human | Others | |
Endothelin-1 is one of the there isoforms of endothelin (identified as ET-1, -2, -3) with varying regions of expression and binding to at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC. | |||
T36479 | Big Endothelin-1 (1-38), human | ||
Human Big ET-1 comprises residues 53-90 of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (hET-1), the peptide show less vasoconstrictor activity in vitro, but similar pressor effects in... | |||
T76329 | [Asn18] Endothelin-1, human | ||
[Asn18] Endothelin-1, human, a peptide, represents a predominant isoform of Endothelin, significantly contributing to the regulation of vascular function [1]. | |||
T15232 | TBC3711 | Endothelin Mordulator 1 | Others |
TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders. | |||
T2026 | CYM5442 | S1P Receptor , LPL Receptor | |
CYM5442 is an S1P agonist, targeting to Sphingosine. | |||
T78063 | Endothelin-1 (1-31) (Human) TFA | ERK | |
Endothelin-1 (1-31) (Human) TFA, a potent vasoconstrictor and hypertensive agent, originates from the chymase-mediated selective hydrolysis of big ET-1 [1]. | |||
T76564 | Endothelin-1 (1-31) (Human) | ||
Endothelin-1 (1-31) (Human) is a powerful vasoconstrictor and agent for inducing hypertension, originating from the specific hydrolysis of big ET-1 by chymase [1]. | |||
TP1512 | [Ala1,3,11,15]-Endothelin TFA | ||
[Ala1,3,11,15]-Endothelin (TFA) is a highly selective for endothelin A (ETA) and endothelin B (ETB) receptor.[Ala1,3,11,15]-Endothelin is a selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for ... | |||
T75731 | Endothelin 1 (swine, human) (TFA) | ||
Endothelin 1 (swine, human) (TFA) is a synthetic peptide mirroring the sequence of the potent endogenous vasoconstrictor found in both human and swine Endothelin 1. It operates via two receptor types, ET A and ET B [1]. | |||
T76564L | Endothelin-1 (1-31) (Human) acetate | ||
Endothelin-1 (1-31) (Human) acetate, a potent vasoconstrictor and hypertensive agent, is produced through the selective hydrolysis of big ET-1 by chymase [1]. | |||
T82886 | Big endothelin-1 (rat 1-39) | ||
Big endothelin-1 (rat 1-39), a 39-residue peptide, induces a diuretic and natriuretic response in conscious Sprague-Dawley rats and elevates blood pressure in mice [1]. | |||
T76081 | Endothelin 1 (swine, human), Alexa Fluor 488-labeled | ||
Endothelin 1 (swine, human), Alexa Fluor 488-labeled, is a synthetic peptide corresponding to the sequence of human and swine Endothelin 1, a powerful endogenous vasoconstrictor, and is tagged with Alexa Fluor 488 for fl... | |||
T6265 | Bosentan (hydrate) | Bosentan Hydrate,Benzenesulfonamide,Actelion,Ro 47-0203 | Endothelin Receptor |
Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors. | |||
T6264 | Bosentan | Actelion,Ro 47-0203,Benzenesulfonamide | Endothelin Receptor |
Bosentan (Benzenesulfonamide) is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks th... | |||
T36008 | Nebentan potassium | ||
Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan . Nebentan potassium inhibits [125I] endothelin-1 binding to cloned ... |